Check-Points

Real-Time detection of carbapenemases and ESBLs

Check-Points
Check-MDR Carba

Detect carbapenemases with high sensitivity and specificity

Check-MDR Carba Detect in a single assay
OXA-48 - IMP - VIM - KPC - NDM More information
Check-MDR ESBL

Detect ESBL with high sensitivity and specificity

Check-MDR ESBL Detect in a single assay
CTX-M - TEM ESBL - SHV ESBL More information
 

Objective results in 4.5 hours
No need for time-consuming interpretation

One accurate test for all clinically prevalent types
Detect carbapenemases or ESBL with high sensitivity and specificity

Use in your Real-Time labflow
Assays utilize existing Real-Time equipment and a standard thermal profile

Download the Check-MDR Carba
product brochure ( .pdf)
Download the Check-MDR ESBL
product brochure ( .pdf)
User manuals
download page

Check-MDR RT workflow

Time per step
Hands-on time per step

1

Culture

2

DNA extraction
Isolate total nucleic acid using automated, magnetic bead or column-based methods (not supplied).
 
 

3

Identification
Ligation-mediated PCR ensures the highly accurate identification of resistance genes.
2 h
10 min

4

Real-Time PCR
Amplification of ligated probes and Real-Time detection though the hybridization of a molecular beacon.
1.5 h
10 min

5

Results
10-20 min
10-20 min

Equipment required

Pre-PCR
  • • Thermocycler*
  • • Vortex Mixer
  • • Mini-centrifuge
  • • PCR plate spinner
Post-PCR
  • • Real-Time PCR instrument*
Reagents required
  • • PCR Master Mix*

* Contact your local representative for specifications

User manuals

Download user manuals

Ordering information

Catalog no. Description
14-0040 Check-MDR ESBL kit, 96 reactions
14-0041 Check-MDR Carba kit, 96 reactions
14-0050 Check-MDR ESBL kit, 24 reactions
14-0051 Check-MDR Carba kit, 24 reactions

Distributors

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For research use only in the US.