Confirm suspected multidrug resistance
Carbapenemases, ESBLs and AmpCs can reduce the susceptibility to antibiotics. Check-MDR CT103 tests isolates against a large number of resistance markers in a single assay, providing you with a comprehensive and timely answer.
Improve your epidemiological insight
Gram-negative antibiotic resistance is increasing worldwide at an alarming rate. Check-MDR CT103 allows you to stay informed on the developments with accurate gene-level information and helps creating a more complete picture by also detecting combinations of resistance genes.
Rapid implementation of infection control measures helps to minimize the impact of outbreaks. Use Check-MDR CT103 as an outbreak investigation tool to potentially exclude outbreaks when the genetic profile of cases differ.
Resistance markers & controls
|Carbapenemases*||CTX-M ESBLs||TEM ESBLs vs. non-ESBL||SHV ESBLs vs. non-ESBL||AmpCs||Controls|
CTX-M-8 & -25 group
CMY II FOX
*All known variants of KPC, NDM and OXA-48 (including OXA-181, 162, 163) reported at www.lahey.org/studies as of March 2012 are detected. VIM variants detected: VIM-1 until -6, VIM-8 until -29. IMP variants detected: IMP-1, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 15, 19, 20, 24, 25.
Check-MDR CT workflow
DNA extractionIsolate total nucleic acid using automated, magnetic bead or column-based methods (not supplied).
IdentificationLigation-mediated PCR ensures the highly accurate identification of resistance genes.
AmplificationOnly ligated probes are amplified.
DetectionProbes hybridize to specific locations on the microarray, contained in a Check-Points Array Tube.
ResultsAn image of the microarray is generated using the Check-Points Tube Reader.
- Vortex Mixer
- Vortex Mixer
- Check-Points Tube Reader including E-Ads software
- Computer with USB drive and internet connection
- Barcode Reader
|10-0020||Check-MDR CT101 kit, 72 reactions|
|10-0019||Check-MDR CT102 kit, 72 reactions|
|10-0021||Check-MDR CT103 kit, 24 reactions|
|16-0012||Check-Points Tube Reader including E-Ads software|
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For research use only in the US.* Contact your local representative for specifications